{"id":2920,"date":"2026-09-06T17:23:53","date_gmt":"2026-09-06T17:23:53","guid":{"rendered":"https:\/\/bookinghospital.org\/?p=2920"},"modified":"2026-09-06T17:34:19","modified_gmt":"2026-09-06T17:34:19","slug":"blood-type-incompatible-kidney-transplant","status":"publish","type":"post","link":"https:\/\/bookinghospital.org\/ro\/blood-type-incompatible-kidney-transplant\/","title":{"rendered":"Blood Type Incompatible Kidney Transplant"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"2920\" class=\"elementor elementor-2920\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5237134 e-con-full e-flex e-con e-parent\" data-id=\"5237134\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f7ccce6 elementor-widget elementor-widget-html\" data-id=\"f7ccce6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div id=\"bh\">\n\n<section class=\"hero\">\n  <div class=\"in\">\n    <p class=\"eyebrow\">Kidney transplantation \u00b7 Before the transplant<\/p>\n    <h1>Your donor's blood type does not match. Now what?<\/h1>\n    <p class=\"lead\">This is where many families are told the conversation ends. It does not\n       have to \u2014 there are two established routes around an incompatible blood type, and\n       both are in use today.<\/p>\n    <p class=\"meta\">Written by <b style=\"color:#fff\">Profesorul Dr. Murat Tuncer<\/b> \u00b7\n       Adapted from his book <i>Kidney Transplantation \u2014 With Questions and Answers<\/i><\/p>\n  <\/div>\n<\/section>\n\n<section class=\"wrap\">\n\n  <div class=\"ozet\">\n    <h2>The short answer<\/h2>\n    <ul>\n      <li>Blood type compatibility is <b>more important than tissue matching<\/b> \u2014 but it is\n          no longer an absolute wall.<\/li>\n      <li><b>Rh factor does not matter.<\/b> A negative donor can give to a positive recipient\n          and the reverse. This is the single most common misunderstanding.<\/li>\n      <li><b>Blood type O donors can donate to anyone.<\/b><\/li>\n      <li>Where blood types are incompatible, two routes exist:\n          <b>ABO-incompatible transplantation<\/b> and <b>paired exchange<\/b>.<\/li>\n      <li>ABO-incompatible transplantation is real but <b>not routine<\/b> \u2014 it is costly, not\n          available in every centre, and reserved for selected patients.<\/li>\n    <\/ul>\n  <\/div>\n\n  <h2>First, the part that is fixed<\/h2>\n\n  <p>There are four blood types: <b>A, B, AB and O<\/b>. Which one you have depends on whether\n     you carry two proteins called the A and B antigens. Carry A, and your type is A. Carry\n     both, and it is AB. Carry neither, and it is O.<\/p>\n\n  <p>These antigens do not sit only on red blood cells \u2014 they are on the surface of all known\n     body cells, acting as an identity card. This is how the immune system tells what belongs\n     to the body from what does not, and it is why blood type carries so much weight in\n     transplantation.<\/p>\n\n  <div class=\"tblwrap\">\n    <table>\n      <thead>\n        <tr><th>If your blood type is<\/th><th>You can receive a kidney from<\/th><\/tr>\n      <\/thead>\n      <tbody>\n        <tr><td><b>O<\/b><\/td><td>O only<\/td><\/tr>\n        <tr><td><b>A<\/b><\/td><td>A or O<\/td><\/tr>\n        <tr><td><b>B<\/b><\/td><td>B or O<\/td><\/tr>\n        <tr><td><b>AB<\/b><\/td><td>Any group \u2014 O, A, B or AB<\/td><\/tr>\n      <\/tbody>\n    <\/table>\n  <\/div>\n\n  <p>Read the table the other way and one thing stands out: a donor with blood type\n     <b>O can donate to anyone<\/b>. That makes O donors valuable, and it also explains why\n     patients with blood type O wait longest \u2014 they can give to everyone but receive only\n     from their own group.<\/p>\n\n  <div class=\"soru\">\n    <h3>My blood type is A Rh negative, my wife's is A Rh positive. Can I donate?<\/h3>\n\n    <p><b>Yes, easily.<\/b> The Rh factor \u2014 the plus or minus after your blood type \u2014 does not\n       matter in kidney transplantation.<\/p>\n\n    <p>A person who is A negative can donate to a recipient who is A negative or A positive.\n       In the same way, both B negative and B positive patients are called for an organ from a\n       B positive deceased donor.<\/p>\n\n    <p>This question comes up constantly, and a surprising number of willing donors have been\n       turned away over it by people who should have known better. If Rh was the stated reason\n       in your case, ask again.<\/p>\n  <\/div>\n\n  <h2>When the blood types genuinely do not match<\/h2>\n\n  <p>In theory, transplantation without blood group compatibility is not possible. The antigens\n     that mark the donor's cells would be read by the recipient's immune system as foreign, and\n     attacked.<\/p>\n\n  <p>Theory and practice, however, often part company. The task of medicine is to reach what\n     looks impossible when a patient's life depends on it \u2014 and in Japan, the United States and\n     Norway, a limited number of transplants between blood-group-incompatible pairs began to be\n     performed.<\/p>\n\n  <div class=\"box\">\n    <span class=\"etiket\">Cum func\u021bioneaz\u0103<\/span>\n    <p>The aim is to introduce the donor's blood type antigen to the recipient as though it\n      were their own. Using filters similar to those in dialysis, the antibodies in the\n      recipient's body that would treat the donor kidney as an enemy are removed.<\/p>\n    <p>Much as dialysis cleans toxic substances from the blood, the process is repeated several\n      times. After that, transplantation may become possible.<\/p>\n  <\/div>\n\n  <div class=\"soru\">\n    <h3>Can this be done for every patient?<\/h3>\n\n    <p><b>No \u2014 and it is important to say so plainly.<\/b> ABO-incompatible transplantation is\n       not a method that can be applied widely, or in every centre.<\/p>\n\n    <ul>\n      <li><b>Outcomes are somewhat lower.<\/b> Ten-year survival of the transplanted kidney is\n          around <b>10% below<\/b> that of blood-type-compatible transplants.<\/li>\n      <li><b>It is expensive.<\/b> The specialised filters used are costly, and several are\n          needed for a single transplant. Reimbursement varies by country and changes over\n          time.<\/li>\n      <li><b>It requires an experienced centre.<\/b> The preparation protocol is demanding and\n          not every transplant unit performs it.<\/li>\n    <\/ul>\n\n    <p>For these reasons it is currently reserved for patients who have <b>no realistic dialysis\n       option<\/b> \u2014 because of vascular problems or previous peritonitis \u2014 or who cannot\n       tolerate dialysis psychologically in any way.<\/p>\n\n    <div class=\"box efsane\">\n      <span class=\"etiket\">An honest limit<\/span>\n      <p>ABO-incompatible transplantation is <b>not an alternative to deceased donor\n        transplantation<\/b>, and it should not be presented as one. It was introduced as a\n        solution for patients who had run out of other options. The wider goal remains\n        increasing the number of transplants from deceased donors.<\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"soru\">\n    <h3>Is there another way around an incompatible pair?<\/h3>\n\n    <p>Yes, and it is often the better first question: <b>paired exchange<\/b>.<\/p>\n\n    <p>If you and your donor are incompatible, and another pair is in the same position, the\n       two donors can be swapped \u2014 your donor gives to the other recipient, and theirs gives to\n       you. Both transplants are blood-type compatible, and neither patient needs the\n       preparation described above.<\/p>\n\n    <p>Exchanges can involve two pairs, or chains of several. A donor with blood type O is\n       particularly valuable in these arrangements, for the reason given earlier.<\/p>\n  <\/div>\n\n  <h2>Where this leaves you<\/h2>\n\n  <p>If you have been told that your donor's blood type rules out a transplant, there are three\n     questions worth putting to your centre, in this order:<\/p>\n\n  <ul>\n    <li><b>Was it really the blood type, or the Rh factor?<\/b> If Rh, the objection does not\n        stand.<\/li>\n    <li><b>Has paired exchange been considered?<\/b> It requires no special preparation and\n        produces a fully compatible transplant.<\/li>\n    <li><b>Is ABO-incompatible transplantation available here?<\/b> If not in your centre, it may\n        be available in another.<\/li>\n  <\/ul>\n\n  <p>None of these guarantee an answer. But \"the blood types do not match\" is the beginning of\n     the assessment, not the end of it.<\/p>\n\n  <div class=\"yazar\">\n    <div class=\"rozet\">MT<\/div>\n    <div>\n      <h3><a href=\"https:\/\/bookinghospital.org\/ro\/murat-tuncer-md\/\" style=\"color:inherit\">Profesorul Dr. Murat Tuncer<\/a><\/h3>\n      <p>Nephrologist and transplant physician. He introduced ABO-incompatible kidney\n        transplantation to T\u00fcrkiye in 2007 and published the first case series; his team also\n        reported the first ABO-incompatible transplants performed in the country. Author of\n        <i>Kidney Transplantation \u2014 With Questions and Answers<\/i> (Istanbul, 2020).<\/p>\n    <\/div>\n  <\/div>\n\n  <div class=\"cta\">\n    <h2>Send us the blood types \u2014 both of them<\/h2>\n    <p>Your blood type, your donor's, and any assessment you have already been given. We will\n       tell you which of the routes above applies to your case, and which do not.<\/p>\n    <div class=\"btns\">\n      <a class=\"btn btn-1\" href=\"https:\/\/bookinghospital.org\/ro\/medical-tourism\/\">Send your medical reports<\/a>\n      <a class=\"btn btn-2\" href=\"https:\/\/bookinghospital.org\/ro\/kidney-transplant-compatibility\/\">Tissue matching explained<\/a>\n    <\/div>\n  <\/div>\n\n  <div class=\"uyari\">\n    <p><b>Medical disclaimer.<\/b> This article is general information adapted from a published\n      book. It is not personal medical advice, it does not establish a doctor\u2013patient\n      relationship, and it cannot replace assessment by the physician treating you. The\n      availability, cost and reimbursement of ABO-incompatible transplantation differ between\n      countries and centres and change over time. Always consult your own nephrologist or\n      transplant centre before making decisions about your treatment.<\/p>\n  <\/div>\n\n  <div class=\"kaynak\">\n    <h3>References<\/h3>\n    <ol>\n      <li class=\"kendi\"><b>Tuncer M<\/b>, et al. ABO-incompatible kidney transplantation: first\n        cases in T\u00fcrkiye. <i>Transplant Proc<\/i> 2012;44(6):1703\u20135.<\/li>\n      <li class=\"kendi\"><b>Tuncer M<\/b>, Gurkan A, Erdogan O, Yucetin L, Demirbas A. Lack of\n        impact of human leukocyte antigen matching in living donor kidney transplantation:\n        experience at Akdeniz University. <i>Transplant Proc<\/i> 2005;37(7):2969\u201372.<\/li>\n      <li>Knoll G, Cockfield S, Blydt-Hansen T, et al. Canadian Society of Transplantation\n        consensus guidelines on eligibility for kidney transplantation.\n        <i>CMAJ<\/i> 2005;173(10).<\/li>\n    <\/ol>\n  <\/div>\n\n<\/section>\n\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Kidney transplantation \u00b7 Before the transplant Your donor&#8217;s blood type does not match. Now what? This is where many families are told the conversation ends. It does not have to \u2014 there are two established routes around an incompatible blood type, and both are in use today. Written by Prof. Dr. Murat Tuncer \u00b7 Adapted [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_joinchat":[],"footnotes":""},"categories":[16],"tags":[],"class_list":["post-2920","post","type-post","status-publish","format-standard","hentry","category-kidney-transplant-guide"],"_links":{"self":[{"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/posts\/2920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/comments?post=2920"}],"version-history":[{"count":4,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/posts\/2920\/revisions"}],"predecessor-version":[{"id":2925,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/posts\/2920\/revisions\/2925"}],"wp:attachment":[{"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/media?parent=2920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/categories?post=2920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bookinghospital.org\/ro\/wp-json\/wp\/v2\/tags?post=2920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}